Mebarki, NoudjoubNabiev, M.Ziane, H.Chader, H.Fazouane, F.2021-05-262021-05-262020Special Issue In celebrating the 10 thanniversary of JFAS1112-9867doi:http://dx.doi.org/10.4314/jfas.v12i1S.1https://dspace.univ-boumerdes.dz/handle/123456789/6947The aim of the present study was to develop and evaluate a topical formulation containingThymus fontanesiiBoiss. & Reutessentialoilthat could serve as an antimicrobial agent forthe treatment of various skin diseases caused by bacteria,yeastanddermatophytes.Theselected formulationexhibited a significant antimicrobial activity against all tested strains,betterconsistency, good homogeneity, no skin irritation and good stabilityforsixmonths at25 ± 2°C.Our results demonstrate thatthe formulationcould beused safely as topicalpreparationto treat skin diseases caused by the tested microorganismsinto the futurefrThymeEssential oilAntimicrobial activitySkin irritationCutaneous infectionsArticle