Browsing by Author "Dob, T."

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    Chemical composition of the essential oil of Salvia officinalis from Algeria
    (Chemistry of Natural Compounds, 2007) Dob, T.; Berramdane, T.; Dahmane, D.; Benabdelkader, T.; Chelghoum, C.
    Sage (Salvia spp.), belonging to the Lamiaceae family, is an aromatic plant and includes about 900 species that grow in several regions all over the world [1]. This genus showed a very high variability of both morphological and cariological characters [2]. Since ancient times, this genus has been used in folk medicine and as a flavoring agent
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    Composition and antimicrobial activity of the essential oil of Thymus fontanesii
    (Pharmaceutical Biology, 2006) Dob, T.; Dahmane, D.; Benabdelkader, T.; Chelghoum, C.
    The yield of oil isolated by hydrodistillation from aerial parts of Thymus fontanesii Boiss. et Reut. (Lamiaceae) growing wild in Djelfa (Algeria) was 0.9%. Analysis of the oil by gas chromatography (GC) and gas chromatography/mass spectrometry (GC/MS) revealed the identification of 47 components accounting for 98.5% of the total oil. The oil was found to be rich in monoterpenes (91.5%) with major constituents being thymol (29.3%), γ-terpinene (21.7%), p-cymene (15.9%), and thymol methyl ether (11.4%), while a smaller amount of linalool (4.8%) and β-caryophyllene (2.9%) were detected. According to the antimicrobial study using the disk diffusion method and the agar dilution assay-minimal inhibitory concentration (MIC), the oil showed strong in vitro growth inhibition activity against Gram-negative bacteria and antifungal activity. The oil exhibited the maximum antifungal activity against Mucor ramaniamus (MIC = 0.2 μL/mL). © 2006 Informa Healthcare
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    Studies on the essential oil composition and antimicrobial activity of Thymus algeriensis Boiss
    (International Journal of Aromatherapy, 2006) Dob, T.; Dahmane, D.; Benabdelkader, T.; Chelghoum, C.
    Many species of Thymus have been widely used in Algerian folk medicine as astringent, expectorant and cicatrising agents. This study was designed to investigate for the first time the essential oil of the aerial parts of wild growing Thymus algeriensis endemic in North Africa. The volatile oil obtained by hydrodistillation was characterized by the physico-chemical properties, GC and GC/MS techniques. The yield of the oil was 1.13% (w/w), based on dry weight. Fifty-five components, representing 94.3% of the total oil, were identified. The oil was distinguished by its high content of oxygenated monoterpenes (79.5%) and was found to possess the following major components: linalool (47.3%), thymol (29.2%) and p-cymene (6.8%). Furthermore, the oil was tested for antimicrobial activity against four bacteria, two fungi and two yeasts. This oil exhibited a significant in vitro antimicrobial activity against Bacillus subtilis (MIC = 0.5 μL/mL), as well as against all yeast and all filamentous fungi tested (MIC = 0.5 and 1.0 μL/mL). © 2006 Elsevier Ltd. All rights reserved