Publications Scientifiques

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Subject: search.filters.subject.Chemical composition

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    Impact of gamma irradiation on phytochemical composition, and biological activities of Lepidium sativum seeds extract
    (Walter de Gruyter GmbH, 2024) Hadj Rabia, Samia; Debib, Aicha; Eddaikra, Atika; Aberkane-Mchebbek, Lila; Nouri, Ramy; Benmoussa, Fatima; Mokhtari, Amine; Medjber, Sarah; Mansouri, Belkacem; Messaoudi, Mohammed
    The main objective of this research is to assess how gamma radiation influences the chemical composition and activities such as antioxidant, antimicrobial and anticancer activities of Lepidium sativum (L. sativum) seeds. Methanolic extracts were obtained through a 24 h maceration process from L. sativum seeds exposed to various doses of gamma irradiation. Phytochemical screening involved precipitation and staining reactions, with the antioxidant potential assessed using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. Antimicrobial activity was evaluated through a diffusion test on agar medium, while the cytotoxic potential on the lung cancer line “A-549 cells” was examined using the 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay. Qualitative analysis of the extracts identified preserved bioactive constituents after irradiation. Additionally, quantitative analysis indicated a significant rise in the total content of polyphenols and flavonoids under radiation, accompanied by an enhanced reducing power compared to the control. The antimicrobial and cytotoxic capabilities also improved, evident in increased growth inhibition zones for certain microbial strains and reduced viability rates of A549 cells. These results show promise and warrant further investigation into the potential of gamma radiation to enhance additional biological effects of plants.
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    Chemical composition and antibacterial activity of rosmarinus officinalis essential oil from algeria
    (2021) Hezil, Djamila; Benseghir, H.; Benamrouche, S.; Zaidi, S.; Zineddine, R.; Bessas, A.; Msela, A.
    The aim of this study was to study the chemical composition and the antibacterial activity of the essential oil (EO) of Rosmarinus officinalis from Blida region, against bacterial strains: Escherichia coli, Staphylococcus epidermis and Pseudomanase fragi. The chemical composition of the EO obtained by hydrodistillation was determined using gas chromatography coupled with mass spectrometry (GC-MS). The antibacterial activity of the EO was studied by the disk diffusion method and the agar dilution method in order to determine the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (CMB). The results obtained from this work show that the yield of rosemary EO was 1.6% respectively. The main compounds present in the essential oil of R. officinalis are 2-Bornanone (19.47%), Eucalyptol (18.58%), α-Pinene (9.14%) and Camphene (5.68%). The MIC and CMB values expressed by the essential oil of R. officinalis were identical as for P.fragi and S. epidermidis (MIC is equal to 0.37% and CMB> 3%) and for E .coli were 0.75% (MIC equals CMB). The results of this work confirmed the activity of the EOs of R. officinalis on the pathogenic bacterial strains tested and to recommend its exploitation for use as an alternative to industrial antibacterial molecules.
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    Investigation of chemical, physical and mechanical properties of algerian date palm wood
    (Carl Hanser Verlag, 2014) Amirou, Siham; Zerizer, Abdellatif; Pizzi, Antonio
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    Chemical composition of the essential oil of Salvia officinalis from Algeria
    (Chemistry of Natural Compounds, 2007) Dob, T.; Berramdane, T.; Dahmane, D.; Benabdelkader, T.; Chelghoum, C.
    Sage (Salvia spp.), belonging to the Lamiaceae family, is an aromatic plant and includes about 900 species that grow in several regions all over the world [1]. This genus showed a very high variability of both morphological and cariological characters [2]. Since ancient times, this genus has been used in folk medicine and as a flavoring agent