Browsing by Author "Villemin, Didier"

Filter results by typing the first few letters
Now showing 1 - 3 of 3
  • No Thumbnail Available
    Item
    An easy synthesis of thermochromic ethylenes under microwave irradiation
    (2003) Villemin, Didier; Hachemi, Messaoud; Hammadi, Mohamed
    Thermochromic ethylenes were obtained by the reaction of anthrone with tricyclic ketones or terephthaldehyde in DMF in the presence of potassium ter-butoxide under reflux (8h) or under microwave irradiation (10 min.)
  • No Thumbnail Available
    Item
    Synthesis of new intercalated quinones and their cytotoxic effects on cancer cell lines
    (2014) Dridi, Feyrel; Bar, Nathalie; Sainte-Catherine, Odile; Hachemi, Messaoud; Lecouvey, Marc; Villemin, Didier
    Naphthoquinones with benzofuran or benzodioxan ring were obtained from dichloronaphthoquinone and were fully characterized. The new benzodioxanes were tested on 4 cancer cells and one of them, a derivative from methyl pyrogallate was found very cytotoxic for cancer cells
  • No Thumbnail Available
    Item
    Tungstosilicic acid (H4SiW12O40) have efficient catalysts for synthesis of 2,3-Dihydroxynaphthoquinone from lawsone
    (2016) Benferrah, Nassima; Hammadi, Mohamed; Dokari, Hadjila; Villemin, Didier
    The Thiele–Winter reaction is of interest for synthesis of tetracetoxyaromatic precursors of hydroxynaphtoquinones. Solid acids such as Tungstosilicic acid (H4 SiW12O40) have an efficient catalyst in acetoxylation reaction of naphtoquinones without the use of organic solvent at room temperature. 1,2,3,4-Tetrahydroxynaphthalene was easily oxidized at room temperature in 2,3-Dihydroxynaphthoquinone by using (Pc[Co]/K10) and air (1 atm). We have also tested this type of reaction in 2-hydroxynaphthoquinone (Lawsone). Many naphthoquinones are natural products with interesting biological properties