Synthesis of new intercalated quinones and their cytotoxic effects on cancer cell lines
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Date
2014
Authors
Dridi, Feyrel
Bar, Nathalie
Sainte-Catherine, Odile
Hachemi, Messaoud
Lecouvey, Marc
Villemin, Didier
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Abstract
Naphthoquinones with benzofuran or benzodioxan ring were obtained from dichloronaphthoquinone and were fully
characterized. The new benzodioxanes were tested on 4 cancer cells and one of them, a derivative from methyl pyrogallate
was found very cytotoxic for cancer cells
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Keywords
Naphthoquinone, Benzofurane, Benzodioxine, Antitumor Activity, Cytotoxicity