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Author: search.filters.author.Boukhalfoun, LeilaHas files: Yes

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    Bioactive compounds and biological activities of Eucalyptus cladocalyx Muell. leaves grown in Bainem forest of Algiers
    (MS-Editions, 2025) Kirouani, Abderrezzak; Boukhalfoun, Leila; Behidj, Nassima
    This study aimed to evaluate the phytochemical composition, antioxidant properties, and antibacterial activities of the essential oil and extracts from Eucalyptus cladocalyx using leaves collected from the Baïnem forest. Essential oil was extracted via hydrodistillation with a Clevenger apparatus, and the methanolic extract was prepared using a rotary evaporator. Prior to analysis, 0.1 µL of the essential oil was diluted in 1:10 hexane solution for GC-MS analysis, which identified 30 constituents, with 1,8-cineole and p-cymene as the primary components. The antioxidant activity assessment demonstrated that the methanolic extract effectively neutralized DPPH, achieving 55% inhibition at a concentration of 500 µg/mL. Furthermore, the essential oil exhibited excellent antibacterial activity against Staphylococcus aureus, Bacillus subtilis, and Klebsiella oxytoca as tested using the aromatogram method, while the methanolic extract showed notable antibacterial activity specifically against Klebsiella oxytoca. These findings suggest that the essential oil of E. cladocalyx has potential applications as a disinfectant in the pharmaceutical industry, while the extracts may serve as a food additive
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    Assessment of Some Biological Activities of Eucalyptus blakelyi Maiden Using the Essential Oil, Methanolic and Aqueous Extracts
    (Har Krishan Bhalla and Sons, 2020) Boukhalfoun, Leila; Kirouani, A.; Behidj, N.; Gana, S.
    Several species of Eucalyptus are used in folk medicine as an antiseptic, anti-inflammatory, and against respiratory infections, such as colds, sinus congestion and influenza. These species have shown potential antioxidant properties in addition to antimicrobial activities. In the present paper, we were interested in Eucalyptus blakelyi Maiden, a species belonging to the Myrtaceae family. Our study can be considered as the first detailed report on the chemical composition, antioxidant and antimicrobial activity of different extracts. The aim of the current study is to evaluate the biological activities of essential oils, methanolic and aqueous extracts of this plant. The present work was realized on leaves collected from National Institute for Forest Research (INRF) of Baïnem (Algiers, Algeria), and the results showed that essential oil’s yield obtained by hydrodistillation was 2.13 %. Actually, 15 compounds were identified by GC-MS profile, and the major compound was 1.8-cineole with 62.74 %. Indeed, the antiradical activity using the DPPH method has shown that methanolic and aqueous extracts had an interesting antioxidant ability with an IC50 of 0.33 and 0.39 mg/ ml respectively. The antimicrobial activity of the essential oil, methanolic and aqueous extracts on eleven microbial strains was evaluated using the aromatogram method. Thus, the methanolic extract proved to be the most active compared to the aqueous extract and the essential oil by inducing a maximum inhibition zones of 19.66 mm for Staphylococcus aureus ATCC29213 and 25.66 mm for Candida albicans. The results suggest potential applications of essential oil in food and extracts in pharmaceutical industry