Publications Internationales

Permanent URI for this collectionhttps://dspace.univ-boumerdes.dz/handle/123456789/13

Browse

Has files: YesSubject: search.filters.subject.Antimicrobial activity

Search Results

Now showing 1 - 9 of 9
  • No Thumbnail Available
    Item
    Algerian wild fennel essential oils: chromatographic profile, acute toxicity, antioxidant, and antimicrobial activities
    (Springer, 2022) Dahman, Karima; Moghrani, Houria; Deghbar, Nahla; Ouare, Salima; Alla, Karim; Arab, Karim
    The present study deals with the characterization of essential oils from umbels and seeds of Algerian wild (bitter) fennel (Foeniculum vulgare Mill. Var vulgare) by determining the chromatographic profile, lethal dose (LD50), antioxidant and antimicrobial activities, as well as a kinetic modeling study of the extraction of the seed-based essential oils. The extrac- tion of essential oils (EOs) was performed by hydrodistillation using Clevenger for 3.5 and 6 h for the umbels and seeds, respectively. The two mathematical models from the experimental data show a good fit with an R2 of 99.99 and 98.94%. GC/ MS analyses of fennel EOs showed that fennel was rich in different oxygenated monoterpenes compounds. However, while fenchone was the main compound in fennel seeds (FSEO), fennel umbel EO (FUEO) mainly contained α-pinene, o-cymene, sylvestrene, fenchone, Endo-fenchyl acetate, and carvacrol. The acute toxicity study of FSEO showed a lethal dose (LD50) of 4.9085 ± 0.1213 g/kg body weight in mice. Based on the free radical scavenging method using BHT as a positive control, the IC50 values were 9.9658 ± 0.057 mg/mL and 0.4570 ± 0.0456 mg/mL for FSEO and BHT, respectively. The study of antimicrobial activity in two gram-negative bacteria: Echerichi coli (ATCC 8739), Pseudomonas aeruginosa (ATCC 9027), and one gram-positive bacterium: Bacilus subtilis (ATCC 6633), as well as two fungal strains: Candida albicans (ATCC 10,231), Saccaromyces cerevisiaes (ATCC 9763), revealed that the fungal strains were more susceptible to FSEO and showed a significant fungicidal effect. The results of this study highlight the high quality of Algerian wild fennel, and the possibility of recovering it for use in the pharmaceutical, cosmetic, and food industries
  • No Thumbnail Available
    Item
    Antimicrobial effect of different organic and aqueous extracts from a lamiaceae; thymus numidicus harvested in bouira (algeria)
    (2017) Behidj-benyounes, N.; Dahmane, T.; Boumghar, N.; Mekhazeni, I; Taki, L.
  • No Thumbnail Available
    Item
  • No Thumbnail Available
    Item
  • No Thumbnail Available
    Item
    Phytochemical screening of Algerian borago officinalis L. and evaluation of its antioxidant and antimicrobial activities against respiratory pathogens
    (Advanced Research Journals, 2014) Afif Chaouche, Thanina; Arab, Karim; Bendahou, Mourad
    Context and purpose of the study: Infectious diseases represent a serious problem of public health in countries where resistance of bacteria to antibiotics is spreading alarmingly. Such situation leads researchers to make efforts so they can isolate or synthesize new antimicrobial molecules or molecules that inhibit the resistance mechanisms. Medicinal plants can represent a rich source of such molecules. In this context, Borago offccinaiis L, a medicinal species which is used traditionally in Algeria to heal infectious diseases of respiratory system is studied. Both of chemical composition and biological activities were explored. Main findings: GC-MS analysis of the essential oil reveals the Spathulenol as the most abundant component (38.24%). The HPLC applied on flavonoids extract shows the presence of the Caffeic acid, p-coumaric acid, Rutin, Rosmarinic acid, Quercetin and the Gallic acid. The test of the antioxidant capacity using the DPPH method reveal an inhibiting effect which is more important with the flavonoid extract with an EC 50 = 4.02± 0.06μg/ml. Otherwise, resistant strains to conventional antibiotics seem to be sensitive to the flavonoids with MICs varying from10.14μg/ml to 81.12μg/ml. Brief summary and potential implications: This study indicates that Borago offccinalss L. has an important antimicrobial effect, which justifies its potential use in infectious diseases. This species remains poorly investigated, further refined studies on its pure secondary metabolites are needed, in the perspective of identifying new antimicrobial molecules from this plant
  • No Thumbnail Available
    Item
    Studies on the essential oil composition and antimicrobial activity of Thymus algeriensis Boiss
    (International Journal of Aromatherapy, 2006) Dob, T.; Dahmane, D.; Benabdelkader, T.; Chelghoum, C.
    Many species of Thymus have been widely used in Algerian folk medicine as astringent, expectorant and cicatrising agents. This study was designed to investigate for the first time the essential oil of the aerial parts of wild growing Thymus algeriensis endemic in North Africa. The volatile oil obtained by hydrodistillation was characterized by the physico-chemical properties, GC and GC/MS techniques. The yield of the oil was 1.13% (w/w), based on dry weight. Fifty-five components, representing 94.3% of the total oil, were identified. The oil was distinguished by its high content of oxygenated monoterpenes (79.5%) and was found to possess the following major components: linalool (47.3%), thymol (29.2%) and p-cymene (6.8%). Furthermore, the oil was tested for antimicrobial activity against four bacteria, two fungi and two yeasts. This oil exhibited a significant in vitro antimicrobial activity against Bacillus subtilis (MIC = 0.5 μL/mL), as well as against all yeast and all filamentous fungi tested (MIC = 0.5 and 1.0 μL/mL). © 2006 Elsevier Ltd. All rights reserved
  • No Thumbnail Available
    Item
    Composition and antimicrobial activity of the essential oil of Thymus fontanesii
    (Pharmaceutical Biology, 2006) Dob, T.; Dahmane, D.; Benabdelkader, T.; Chelghoum, C.
    The yield of oil isolated by hydrodistillation from aerial parts of Thymus fontanesii Boiss. et Reut. (Lamiaceae) growing wild in Djelfa (Algeria) was 0.9%. Analysis of the oil by gas chromatography (GC) and gas chromatography/mass spectrometry (GC/MS) revealed the identification of 47 components accounting for 98.5% of the total oil. The oil was found to be rich in monoterpenes (91.5%) with major constituents being thymol (29.3%), γ-terpinene (21.7%), p-cymene (15.9%), and thymol methyl ether (11.4%), while a smaller amount of linalool (4.8%) and β-caryophyllene (2.9%) were detected. According to the antimicrobial study using the disk diffusion method and the agar dilution assay-minimal inhibitory concentration (MIC), the oil showed strong in vitro growth inhibition activity against Gram-negative bacteria and antifungal activity. The oil exhibited the maximum antifungal activity against Mucor ramaniamus (MIC = 0.2 μL/mL). © 2006 Informa Healthcare
  • No Thumbnail Available
    Item
    Essential oils from wild populations of algerian lavandula stoechas L. : composition, chemical variability, and in vitro biological properties
    (Wiley Periodicals, 2011) Benabdelkader, Tarek; Zitouni, Abdelghani; Guitton, Yann; Jullien, Frédéric; Maitre, Dany; Casabianca, Hervé; Legendre, Laurent; Kameli, Abdelkrim
  • No Thumbnail Available
    Item
    Preparation and biological characterization of cellulose graft copolymers
    (Elsevier, 2010) Dahou, Wassila; Ghemati, Djamila; Oudia, Atika; Aliouche, Djamel
    Acrylic acid (AA) and acrylonitrile (AN) were graft polymerized onto cellulose fluff pulp using cericammonium nitrate as initiator. The resulting copolymers were saponified with dilute sodium hydroxide and characterized by FT-IR, SEM and TGA. The potential value of the modified cellulose was assessed through measurements of absorbency properties. A fibre-hydrogel was prepared by an addition of a bifunctional monomer, ethyleneglycol dimethacrylate (EDMA) used for grafting. In second approach, biocide cellulose carbamate was prepared by impregnating the fibres in aqueous thiourea solution and subsequent grafting with acrylonitrile. Antimicrobial activity of the treated cellulose sample was studied against Escherichia coli, Pseudomonas aeruginosa and Bacillus subtilis according to AATCC test method 100–1999. The results show that the treated fibre gives higher antimicrobial activity. The strong antimicrobial functions achieved on modified fibres, proved that the synthesized biomaterial was effective, very simple and practical to the textile finishing industry