Synthesis of 1, 3-oxathiolanes without use of organic solvent at room temperature. Remarkable functional selectivity

Abstract

The aluminosilicates acids are efficient catalysts for the synthesis of oxathiolanes without solvent at room temperature. A functional selectivity was observed between aldehydes and ketones, aldehydes were transformed quantitatively. A functional selectivity has not been described before, it was observed within differents aldehydes or within differents ketones. This selectivity is important for the control of the reactions (activation or protection) of carbonyl compounds in organic synthesis