Etude phytochimique et évaluation de l’activité anti-inflammatoire et cicatrisante des extraits de Carthamus caeruleus L.

Abstract

The main objective of this work is the evaluation of the anti-inflammatory and anti-healing activity using the aqueous extract and the traditional cream of the medicinal plant Carthamus caeruleus L. A synthesis of previous work allowed us to deduce that this plant is very rich in secondary metabolites mainly flavonoids, saponins, coumarins, leuco-anthocyanins and alkaloids. The best yield and dosage values are obtained from the ethanolic extract (15.2% and 53.36 ± 0.51 mg EGA / g of extract respectively). In addition, all the results show that the methanolic extract of safflower is endowed with a powerful anti-inflammatory effect with a percentage of inhibition of edema of 92.20%. Regarding the results of the healing activity, the wounds treated with the traditional cream prepared by the rhizomes of Carthamus caeruleus L. were distinguished by their better healing (98.33%; 99.32% and 100%).